Immediate Early Genes and Inducible Transcription Factors in Mapping of the Central Nervous System Function and Dysfunction Ebook

, L. Kaczmarek , H.A. Robertson , H. A. Robertson
Publication: Elsevier Science
 
Is my Device Supported?

You're about to purchase a Downloadable Ebook

Hi, sorry for the interruption!
We're repeating some important information here to ensure that you're making an informed purchase. Please review it.

  • Don't get caught unaware. Preview ebook and open the sample ebook on each of your intended devices before continuing.
  • You will need a Free 3rd-party application that can read the intermediate .acsm file you will receive as download. PDF/Epub format is downloaded automatically by the application thereafter. Please install the necessary software first on your intended device of use.
  • - Printing is not permitted.
    - You cannot copy text from file.
  • Refund Policy
    Refunds are not allowed after the ebook is opened so please open the ebook directly on your intended device. Refund requests should be recieved within 7 days after download is made available. Of course, if you get an incorrect ebook ( different from what is mentioned in the title) or if the ebook doesn't open on the initial device, then we'll assist with fixing the issue or get you a refund if a timely fix isn't available.
  • Customer Service
    We currently only provide ticket (online form submission) or email support. Rest assured that you're in good hands; customers like our professional service!
I have previewed the ebook and read the requirements and terms.
Cancel

Language: English
Publication Date: July 2002
File Size: 38622 Kbytes

Restrictions set by Publisher:
- Text-to-speech feature not available.
- Printing is not permitted.
- You cannot copy text from file.
- Free application Adobe Digital Editions, Aldiko reader, or Bluefire reader required .
$341.30 $375.00
( 8.99% savings )

Great Prices, Always!
Change Region
 
ISBN: 9780080534466   Should I buy this Ebook?   Write a Review

Description

That molecular neurobiology has become a dominant part of neuroscience research can be credited to the discovery of inducible gene expression in the brain and spinal cord. This volume deals with genes, whose expression patterns in the vertebrate central nervous system were the first to be revealed and then the most extensively investigated over the last 15 years. Immediate early genes (IEG) and their protein products, especially those acting as regulators of transcription (inducible transcription factors, ITF) have proven to be very valuable tools in functional neuroanatomy and neurophysiology, as they are rapidly and transiently induced in specific neurons in response to various modes of stimulation. Thus, they have been used to map neuronal populations selectively responsive to a variety of conditions, such as sensory and learning experience, electrical stimulation of specific circuits, seizures, and neurodegeneration.

This single volume, written by the most prominent authors in the field, brings together for the first time information about the most widely studied IEG/ITF in a whole variety of phenomena of neuronal activation. It starts with a critical appraisal of the technologies employed for the studies on gene, protein, and transcription factor activity in the nervous system. Several chapters present exhaustive examples of expression patterns of the ITF in “vocal” avian brain, mammalian brain sensory regions, areas involved in regulation of circadian rhythms, and the spinal cord. The next parts cover functional and regular aspects of individual IEG/ITF expression: c-fos in learning and memory, c-jun and others in neuropathology and neuronal stress responses, Elk-1, egr family, and CREB in neuronal plasticity and learning.

This volume will be useful as a major reference on this topic. Furthermore, it attempts to unravel the seemingly overwhelming complexity of the phenomena of gene expression in the central nervous system.

Recommendations:

Handbook of Categorization in Cognitive Science ebook cover
Save 7.91%
Consciousness Transitions: Phylogenetic, Ontogenetic and Physiological Aspects ebook cover
Save 5.99%
The Memory Cure: How to Protect Your Brain Against Memory Loss and Alzheimer's Disease ebook cover
Save 17.35%
Evolutionary Developmental Biology of the Cerebral Cortex ebook cover
Save 9.56%
Proteins of the Cerebrospinal Fluid ebook cover
Save 7.91%

Should you buy this Ebook?

We've put together a collection of resources to help you make a decision regarding whether you should buy this Ebook from us.

  1. Is your device one of these? Ebook reading software will work on the following devices: Windows, Mac, Android 2.2+ Devices, IPad (iOS 3+), IPhone (iOS 3+), Kindle Fire. Several other devices are also supported by the software.
  2. Compare prices. Our price is $341.30. If you would like to research our competitors to see their prices. Here're some places to look:
  3. Why should you buy Ebooks from onlinebookplace.com?

    We've had 1000s of downloads so far and with over 300000+ Ebooks to choose from, onlinebookplace.com is becoming a favorite Ebook Store for many. Allow us to win you over with our competitive pricing, upfront policies and diligent customer service.

    We're Upfront:

    • Every Ebook page on onlinebookplace.com has information on restrictions that publishers have placed on the Ebook along with a clear indication of software required to read the Ebooks.
    • If ratings for an Ebook are available from one of several sources online, then we've attempted to get those to help you make a better purchasing decision about the Ebook. Reviews from Goodreads (a popular reviews site) are provided on the same if they're available.
    • In most cases, we've also attempted to get you links to the Ebook on our competitor's site so that you can compare prices with relative ease.
    • We use McAfee to scan for any vulnerabilities in the system to ensure that any information that you give us does not fall into the wrong hands.
    • We use Paypal, a trusted 3rd party payment provider to accept Payments -- your payment information doen't reside with us. Any information that does end up with us is safe.

After installing the appropriate app for your device, try a Sample Download (Sherlock Holmes from Project Gutenberg) before purchase. The sample is only for checking device compatibility.

Check below for device compatibility and any free 3rd-party software requirements. Choice of what ebook reading app to use is yours, we only present a few common apps that several customers of ours have preferred. You should be able to transfer your purchase to more than one (upto 6) compatible devices as long as your ebook-reading apps have been registered with the same Adobe ID before opening the file.

Computers/laptops/Mac

Windows/Mac PC or Laptop

Free app Adobe Digital Editions required. Note that this software is not the same as Adobe Reader.

Android

Android 2.1+

Free app Aldiko Reader or Bluefire Reader required.

Kindle Fire (and any Android based Kindle models)

Free Kindle Android app Bluefire Reader required.

IPhone/IPad

IPad or IPhone

Free app Bluefire Reader required. Kindly review their tutorial for the requirement (note that while they're talking about library ebooks, same applies to your purchased .acsm file) -- feel free to use the sample download for testing. Tutorial .

Other E-Reader

Several Other devices supported

Devices like Nook are supported via the free application Adobe Digital Editions . This software is not the same as Adobe Reader. Please check compatibility of your device before purchase.

Immediate Early Genes and Inducible Transcription Factors in Mapping of the Central Nervous System Function and Dysfunction