Protein Targeting to Mitochondria Ebook
You're about to purchase a Downloadable Ebook
Hi, sorry for the interruption!
We're repeating some important information here to ensure that you're making an informed purchase. Please review it.
- Don't get caught unaware. Preview ebook and open the sample ebook on each of your intended devices before continuing.
- You will need a Free 3rd-party application that can read the intermediate .acsm file you will receive as download. PDF/Epub format is downloaded automatically by the application thereafter. Please install the necessary software first on your intended device of use.
- Printing is permitted.
- You can copy text from file.
Refunds are not allowed after the ebook is opened so please open the ebook directly on your intended device. Refund requests should be recieved within 7 days after download is made available. Of course, if you get an incorrect ebook ( different from what is mentioned in the title) or if the ebook doesn't open on the initial device, then we'll assist with fixing the issue or get you a refund if a timely fix isn't available.
We currently only provide ticket (online form submission) or email support. Rest assured that you're in good hands; customers like our professional service!
Publication Date: February 1997
File Size: 22872 Kbytes
Restrictions set by Publisher:
- Text-to-speech feature not available.
- Printing is permitted.
- You can copy text from file.
- Free application Adobe Digital Editions, Aldiko reader, or Bluefire reader required .
- Check Supported devices and software requirements .
- Ebooks once opened are non-refundable. View return policy .
- OnlineBookPlace.com Store Reviews on Google and Yahoo
A large number of newly-synthesized polypeptides must cross one or several intracellular membranes to reach their functional locations in the eukaryotic cell. The mechanisms of protein trafficking, in particular the post-translational targeting and membrane translocation of proteins, are of fundamental biological importance and are the focus of intensive research world-wide. For more than 15 years, mitochondria have served as the paradigm organelle system to study these processes. Although key questions, such as how precisely proteins cross a membrane, still remain to be answered, exciting progress has been made in understanding the basic pathways of protein import into mitochondria and the components involved. In addition to a fascinating richness and complexity in detail, the analysis of mitochondrial protein import has revealed mechanistic principles of general significance: Major discoveries include the demonstration of the requirement of an unfolded state for translocation and of the essential role of molecular chaperones on both sides of the membranes in maintaining a translocation-competent conformation and in protein folding after import. It is becoming clear how a polypeptide chain is “reeled” across the membrane in an ATP-dependent process by the functional cooperation of membrane proteins, presumably constituting part of a transmembrane channel, with peripheral components at the trans-side of the membrane.
In this volume, eminent experts in the field take the time to review the central aspects of mitochondrial biogenesis. The logical order of the 16 chapters is determined by the sequence of steps during protein import, starting with the events taking place in the cytosol, followed by the recognition of targeting signals, the translocation of precursor proteins across the outer and inner membranes, their proteolytic processing and intramitochondrial sorting, and finally their folding and oligomeric assembly. In addition, the mechanisms involved in the export of mitochondrially encoded proteins as well as recent advances in understanding the division and inheritance of mitochondria will be discussed.
Should you buy this Ebook?
We've put together a collection of resources to help you make a decision regarding whether you should buy this Ebook from us.
- Is your device one of these? Ebook reading software will work on the following devices: Windows, Mac, Android 2.2+ Devices, IPad (iOS 3+), IPhone (iOS 3+), Kindle Fire. Several other devices are also supported by the software.
- Compare prices. Our price is $135.80. If you would like to research our competitors to see their prices. Here're some places to look:
Why should you buy Ebooks from onlinebookplace.com?
We've had 1000s of downloads so far and with over 300000+ Ebooks to choose from, onlinebookplace.com is becoming a favorite Ebook Store for many. Allow us to win you over with our competitive pricing, upfront policies and diligent customer service.
- Every Ebook page on onlinebookplace.com has information on restrictions that publishers have placed on the Ebook along with a clear indication of software required to read the Ebooks.
- If ratings for an Ebook are available from one of several sources online, then we've attempted to get those to help you make a better purchasing decision about the Ebook. Reviews from Goodreads (a popular reviews site) are provided on the same if they're available.
- In most cases, we've also attempted to get you links to the Ebook on our competitor's site so that you can compare prices with relative ease.
- We use McAfee to scan for any vulnerabilities in the system to ensure that any information that you give us does not fall into the wrong hands.
- We use Paypal, a trusted 3rd party payment provider to accept Payments -- your payment information doen't reside with us. Any information that does end up with us is safe.
After installing the appropriate app for your device, try a Sample Download (Sherlock Holmes from Project Gutenberg) before purchase. The sample is only for checking device compatibility.
Check below for device compatibility and any free 3rd-party software requirements. Choice of what ebook reading app to use is yours, we only present a few common apps that several customers of ours have preferred. You should be able to transfer your purchase to more than one (upto 6) compatible devices as long as your ebook-reading apps have been registered with the same Adobe ID before opening the file.
Windows/Mac PC or Laptop
Free app Adobe Digital Editions required. Note that this software is not the same as Adobe Reader.